Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7396173 | 1.00 | KDM2B (0.43) | KDM2BKMT2AMEN1MAPTALDH1A1 | |
| Oxalic Acid SCHEMBL467153 | 0.88 | DRD4 (0.40) | KMT2AALDH1A1LMNAKDM4EALOX12 | |
| Oxalic Acid SCHEMBL467154 | 0.88 | DRD4 (0.40) | KMT2AALDH1A1LMNAKDM4EALOX12 | |
| Oxalic Acid SCHEMBL7401973 | 0.72 | KDM2B (0.44) | KDM2BKMT2AMEN1MAPTALDH1A1 | |
| Oxalic Acid SCHEMBL7401971 | 0.72 | KDM2B (0.44) | KDM2BKMT2AMEN1MAPTALDH1A1 | |
| Oxalic Acid SCHEMBL7364061 | 0.70 | KDM4E (0.37) | KDM2BALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13268902 | 0.69 | SMN1; SMN2 (0.64) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28121003 | 0.68 | SMN1; SMN2 (0.58) | ALDH1A1HTTKDM4ESMN1; SMN2HPGD | |
| SCHEMBL8215476 | 0.67 | KMT2A (0.39) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL466882 | 0.66 | KMT2A (0.40) | KMT2AMEN1ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208343-A | Antidepressants, antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | claimed |
| WO-1993019047-A1 | TETRAHIDROPYRIDINYL (3/4) SUBSTITUED OXIMES HAVING SIGMA RECEPTOR AFFINITY AND THEIR USE IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM CONDITIONS | WARNER-LAMBERT COMPANY (US) | 1993-09-30 | — | — | WO | disclosed |
| US-5208343-A | Antidepressants, antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |