SCHEMBL7396258

SCHEMBL7396258

N#Cc1ccc(C(=O)NCCCCN2CCC[C@H]3c4cc(C#N)ccc4OC[C@@H]32)cc1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 20/20 0.59
DRD3 P35462 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7396260 1.00 DRD2 (0.59) DRD2DRD3
Hydrochloric Acid SCHEMBL7690464 0.99 DRD2 (0.59) DRD2DRD3
Hydrochloric Acid SCHEMBL7690462 0.99 DRD2 (0.59) DRD2DRD3
SCHEMBL7392936 0.95 DRD2 (0.57) DRD2DRD3
SCHEMBL7392938 0.95 DRD2 (0.57) DRD2DRD3
Hydrochloric Acid SCHEMBL7687931 0.94 DRD2 (0.56) DRD2DRD3
Hydrochloric Acid SCHEMBL7687933 0.94 DRD2 (0.56) DRD2DRD3
Hydrochloric Acid SCHEMBL7683753 0.93 DRD2 (0.69) DRD2DRD3
Hydrochloric Acid SCHEMBL7683756 0.93 DRD2 (0.69) DRD2DRD3
SCHEMBL7391560 0.80 DRD2 (0.87) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0887350-B1 Chromene derivatives, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 2001-08-22 EP disclosed