SCHEMBL7396261

SCHEMBL7396261

CC(NC(=O)CCn1cnc2c(=O)[nH]cnc21)N1CCCC1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 17/20 0.48
PNP P00491 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7403481 0.99 HPRT1 (0.47) HPRT1PNP
SCHEMBL7982599 0.85 TK1 (0.52) HPRT1PNP
SCHEMBL7980534 0.84 TK1 (0.51) HPRT1PNP
SCHEMBL7396262 0.79 HPRT1 (0.51) HPRT1PNP
SCHEMBL7403479 0.78 HPRT1 (0.50) HPRT1PNP
SCHEMBL7397072 0.77 HPRT1 (0.59) HPRT1PNP
SCHEMBL7394846 0.77 HPRT1 (0.46) HPRT1PNP
SCHEMBL7398541 0.76 HPRT1 (0.55) HPRT1PNP
SCHEMBL7684892 0.75 HPRT1 (0.67) HPRT1PNP
SCHEMBL7392166 0.75 HPRT1 (0.54) HPRT1PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991014434-A1 MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE GLASKY ALVIN J (US) 1991-10-03 WO disclosed