Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339770 | 0.81 | F2 (0.43) | GAAF2F10PRSS1KMT2A | |
| SCHEMBL7339777 | 0.81 | F2 (0.43) | GAAF2F10PRSS1KMT2A | |
| SCHEMBL10907376 | 0.80 | F2 (0.40) | GAAF2F10PRSS1NFKB1 | |
| SCHEMBL10907374 | 0.80 | F2 (0.40) | GAAF2F10PRSS1NFKB1 | |
| SCHEMBL7347648 | 0.80 | F2 (0.42) | GAAF2F10PRSS1KMT2A | |
| SCHEMBL8837660 | 0.80 | ACE (0.48) | GAAF2F10PRSS1KMT2A | |
| SCHEMBL8837664 | 0.80 | ACE (0.48) | GAAF2F10PRSS1KMT2A | |
| SCHEMBL8837673 | 0.80 | ACE (0.48) | GAAF2F10PRSS1KMT2A | |
| SCHEMBL7350194 | 0.79 | F2 (0.42) | GAAF2F10PRSS1KMT2A | |
| SCHEMBL7350200 | 0.79 | F2 (0.42) | GAAF2F10PRSS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000055156-A1 | SUBSTITUTED AROMATIC AMIDINE DERIVATIVE AND MEDICINAL COMPOSITION COMPRISING THE SAME | C & C RESEARCH LABORATORIES (KR) | 2000-09-21 | — | — | WO | disclosed |