SCHEMBL7396366

SCHEMBL7396366

CCCC(NC(=O)NC(C)C)P(=O)(O)CN(C(=O)CCCc1ccccc1)[C@@H](CC(C)C)C(=O)Nc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 19/20 0.42
MMP2 P08253 6/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7396368 0.81 MMP3 (0.54) MMP3MMP2
SCHEMBL8858194 0.80 MMP3 (0.39) MMP3MMP2
SCHEMBL7394769 0.75 MMP3 (0.44) MMP3MMP2
SCHEMBL7402164 0.74 MMP3 (0.51) MMP3MMP2
SCHEMBL7398821 0.74 MMP3 (0.40) MMP3MMP2
SCHEMBL7643934 0.74 MMP3 (0.48) MMP3MMP2
SCHEMBL7391702 0.72 MMP3 (0.64) MMP3MMP2
SCHEMBL7394771 0.72 MMP3 (0.55) MMP3MMP2
SCHEMBL7397284 0.72 MMP3 (0.40) MMP3MMP2
SCHEMBL7398823 0.70 MMP3 (0.43) MMP3MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623143-A1 SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS MERCK & CO. INC. (US) 1994-11-09 EP disclosed
WO-1993014112-A1 SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS MERCK & CO., INC. (US) 1993-07-22 WO disclosed