Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 15/20 | 0.75 |
| ▸ | AGTR2 | P50052 | 15/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398430 | 0.91 | AGTR1 (0.74) | AGTR1AGTR2 | |
| SCHEMBL9033077 | 0.90 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL7398978 | 0.90 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL7828850 | 0.89 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL7398754 | 0.89 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL7828364 | 0.89 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL7398914 | 0.89 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL7818972 | 0.89 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL7826759 | 0.88 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL7829313 | 0.88 | AGTR1 (0.69) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018888-A1 | N-SUBSTITUTED-1,2,4-TRIAZOLONE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-12 | — | — | WO | claimed |
| WO-1991018888-A1 | N-SUBSTITUTED-1,2,4-TRIAZOLONE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-12 | — | — | WO | disclosed |