Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.58 |
| ▸ | ECE1 | P42892 | 11/20 | 0.58 |
| ▸ | CTSC | P53634 | 1/20 | 0.52 |
| ▸ | GHSR | Q92847 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397057 | 1.00 | ACE (0.58) | ACEECE1CTSCGHSR | |
| SCHEMBL7446375 | 0.95 | ACE (0.54) | ACEECE1CTSCGHSR | |
| SCHEMBL7394083 | 0.95 | ACE (0.54) | ACEECE1CTSCGHSR | |
| SCHEMBL7394085 | 0.95 | ACE (0.54) | ACEECE1CTSCGHSR | |
| SCHEMBL30838790 | 0.92 | ACE (0.67) | ACEECE1 | |
| SCHEMBL23312954 | 0.92 | ECE1 (0.67) | ACEECE1CTSC | |
| SCHEMBL23312953 | 0.91 | ECE1 (0.58) | ACEECE1CTSCGHSR | |
| SCHEMBL30725664 | 0.90 | ACE (0.70) | ACEECE1 | |
| SCHEMBL30725658 | 0.88 | ACE (0.56) | ACEECE1 | |
| SCHEMBL30051826 | 0.88 | ACE (0.68) | ACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | claimed |