Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 6/20 | 0.58 |
| ▸ | GHSR | Q92847 | 4/20 | 0.57 |
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | CTSC | P53634 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 4/20 | 0.53 |
| ▸ | MMP8 | P22894 | 4/20 | 0.53 |
| ▸ | MMP1 | P03956 | 3/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30052328 | 0.93 | ACE (0.60) | ECE1ACECTSCMMP9MMP8 | |
| SCHEMBL23312954 | 0.93 | ECE1 (0.67) | ECE1ACECTSCMMP9MMP8 | |
| SCHEMBL7397057 | 0.91 | ACE (0.58) | ECE1GHSRACECTSC | |
| SCHEMBL7397063 | 0.91 | ACE (0.58) | ECE1GHSRACECTSC | |
| SCHEMBL30051826 | 0.91 | ACE (0.68) | ECE1ACE | |
| SCHEMBL29555460 | 0.89 | ACE (0.66) | ECE1ACE | |
| SCHEMBL3512696 | 0.89 | ACE (0.71) | ECE1ACE | |
| SCHEMBL5481232 | 0.89 | ACE (0.71) | ECE1ACE | |
| SCHEMBL8725890 | 0.89 | ACE (0.71) | ECE1ACE | |
| SCHEMBL7397641 | 0.89 | ACE (0.71) | ECE1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10993983-B2 | Cyclic peptide epitopes and small-molecule mimics for inducing autophagy | TRUSTEES OF TUFTS COLLEGE (US) | 2021-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10993983-B2 | Cyclic peptide epitopes and small-molecule mimics for inducing autophagy | BECN1, SQSTM1, ATG7 | ECE1 2223/4885GHSR 2345/4885ACE 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.