Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397122 | 1.00 | RAB9A (0.61) | RAB9AFKBP1AHTTMEN1KMT2A | |
| SCHEMBL4052147 | 0.84 | RAB9A (0.56) | RAB9AFKBP1AHTTMEN1KMT2A | |
| SCHEMBL3592470 | 0.76 | RAB9A (1.00) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL3592465 | 0.76 | RAB9A (1.00) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL9298956 | 0.74 | MAOB (0.61) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19MAPT | |
| SCHEMBL6666145 | 0.74 | MAPK1 (0.57) | RAB9AFKBP1AHTTMEN1KMT2A | |
| SCHEMBL1516144 | 0.72 | MAPT (0.82) | RAB9AFKBP1AMEN1KMT2ANPSR1 | |
| SCHEMBL4049634 | 0.72 | RAB9A (0.71) | RAB9AFKBP1AMEN1KMT2AALDH1A1 | |
| SCHEMBL24268665 | 0.72 | RAB9A (0.47) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL21889705 | 0.72 | RAB9A (0.47) | RAB9ANPSR1ALDH1A1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000972-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-01-23 | — | — | WO | disclosed |