Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397201 | 1.00 | FOLH1 (0.33) | FOLH1METAP2METAP1ENPEPCYP1A2 | |
| SCHEMBL7399057 | 0.86 | RNPEP (0.44) | FOLH1ENPEPCYP1A2 | |
| SCHEMBL7399053 | 0.86 | RNPEP (0.44) | FOLH1ENPEPCYP1A2 | |
| Amantadine SCHEMBL7398902 | 0.84 | THRB (0.34) | — | |
| Amantadine SCHEMBL7398905 | 0.84 | THRB (0.34) | — | |
| SCHEMBL7396782 | 0.84 | ACE (0.35) | ENPEP | |
| SCHEMBL7396783 | 0.84 | ACE (0.35) | ENPEP | |
| SCHEMBL9236581 | 0.84 | ACE (0.35) | ENPEP | |
| SCHEMBL7436044 | 0.81 | MME (0.35) | METAP2 | |
| SCHEMBL7436049 | 0.81 | MME (0.35) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | claimed |
| US-5348978-A | Angiotensin converting enzyme inhibitors | FISONS PLC (GB) | 1994-09-20 | — | — | US | claimed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | claimed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | claimed |