Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.76 |
| ▸ | ITGAV | P06756 | 16/20 | 0.76 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244300 | 0.86 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7211729 | 0.85 | ITGB3 (0.55) | ITGB3ITGAVITGA2BPOLB | |
| SCHEMBL7217714 | 0.76 | ITGB3 (0.46) | ITGB3ITGAVITGA2BMALT1 | |
| SCHEMBL7216485 | 0.74 | ITGB3 (0.86) | ITGB3ITGAVITGA2B | |
| SCHEMBL7211708 | 0.74 | ITGB3 (0.76) | ITGB3ITGAVITGA2BLMNA | |
| SCHEMBL7212645 | 0.71 | ITGB3 (0.60) | ITGB3ITGAVITGA2BPOLBLMNA | |
| SCHEMBL606799 | 0.71 | ITGB3 (0.58) | ITGB3ITGAVITGA2BPOLBLMNA | |
| SCHEMBL7392649 | 0.71 | ITGB3 (0.74) | ITGB3ITGAVITGA2B | |
| SCHEMBL7211723 | 0.71 | ITGB3 (0.74) | ITGB3ITGAVITGA2B | |
| SCHEMBL7217497 | 0.70 | ITGB3 (0.92) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796855-B1 | Inhibitors of bone resorption and vitronectin receptor antagonists | HOECHST AG (DE) | 2002-02-06 | — | — | EP | disclosed |
| EP-0796855-A1 | Inhibitors of bone resorption and vitronectin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-24 | — | — | EP | disclosed |