Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 14/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 14/20 | 0.44 |
| ▸ | ACE | P12821 | 13/20 | 0.44 |
| ▸ | CPA1 | P15085 | 13/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429304 | 0.88 | MME (0.51) | MMEACE2ACECPA1 | |
| SCHEMBL6162707 | 0.78 | MME (0.51) | ADRB2MMEACE2ACECPA1 | |
| SCHEMBL6161923 | 0.78 | MME (0.51) | ADRB2MMEACE2ACECPA1 | |
| SCHEMBL7397406 | 0.78 | ADRB2 (0.41) | ADRB2MMEACE2ACECPA1 | |
| SCHEMBL6161590 | 0.74 | MME (0.66) | MME | |
| SCHEMBL6161582 | 0.74 | MME (0.66) | MME | |
| SCHEMBL6574501 | 0.74 | MME (0.66) | MME | |
| SCHEMBL3410335 | 0.74 | MME (0.66) | MME | |
| SCHEMBL7315829 | 0.74 | MME (0.66) | MME | |
| SCHEMBL6162737 | 0.72 | MME (0.53) | MMEACE2ACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877740-A1 | THIOL DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1998-11-18 | — | — | EP | claimed |
| WO-1997024342-A1 | THIOL DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1997-07-10 | — | — | WO | claimed |