Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.45 |
| ▸ | ITGAV | P06756 | 4/20 | 0.45 |
| ▸ | RORC | P51449 | 7/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397715 | 1.00 | ITGB3 (0.45) | ITGB3ITGAVRORCBRD4CREBBP | |
| SCHEMBL7394572 | 0.77 | ITGB3 (0.58) | ITGB3ITGAV | |
| SCHEMBL7438965 | 0.75 | NPC1 (0.47) | ITGB3 | |
| SCHEMBL7438972 | 0.75 | NPC1 (0.47) | ITGB3 | |
| SCHEMBL7075297 | 0.74 | ITGB3 (0.57) | ITGB3ITGAV | |
| SCHEMBL7917703 | 0.74 | ITGB3 (0.50) | ITGB3ITGAV | |
| SCHEMBL7398006 | 0.74 | ITGB3 (0.50) | ITGB3ITGAV | |
| SCHEMBL7917671 | 0.74 | ITGB3 (0.50) | ITGB3ITGAV | |
| SCHEMBL7397999 | 0.74 | ITGB3 (0.50) | ITGB3ITGAV | |
| SCHEMBL7917665 | 0.74 | ITGB3 (0.50) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6127359-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |