SCHEMBL7397828

SCHEMBL7397828

CC(C)CC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)N(C)C(=O)[C@H](Cc1ccccc1)OC(=O)N(C)CCC(=O)N1CCOCC1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9354482 0.99 REN (0.53) REN
SCHEMBL9354929 0.98 REN (0.53) REN
SCHEMBL9354502 0.97 REN (0.52) REN
SCHEMBL7393624 0.95 REN (0.59) REN
Hydrochloric Acid SCHEMBL9288472 0.94 REN (0.59) REN
SCHEMBL9354954 0.94 REN (0.57) REN
SCHEMBL9354463 0.94 REN (0.57) REN
SCHEMBL9354410 0.93 REN (0.56) REN
SCHEMBL9358260 0.93 REN (0.50) REN
SCHEMBL9354589 0.93 REN (0.46) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300189-B1 New amino acid derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO (JP) 1994-11-02 EP claimed
EP-0573652-A1 REMEDY FOR RENAL DISEASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-12-15 EP claimed
JP-1019071-A None JP disclosed
EP-0300189-B1 New amino acid derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO (JP) 1994-11-02 EP disclosed
WO-1993012796-A1 USE OF RENIN INHIBITORS FOR THE TREATMENT OF GLAUCOMA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-07-08 WO disclosed
EP-0300189-A2 New amino acid derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-01-25 EP disclosed