Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11898133 | 0.83 | MAPK10 (0.75) | MAPK10KMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL24489078 | 0.82 | MAPK10 (1.00) | MAPK10KMT2ASMN1; SMN2MEN1TDP1 | |
| SCHEMBL4703988 | 0.81 | KDM4E (1.00) | MAPK10KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL16674539 | 0.78 | KDM4E (0.70) | MAPK10KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14095084 | 0.78 | KDM4E (0.74) | MAPK10KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11578842 | 0.78 | KMT2A (0.69) | MAPK10KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3702839 | 0.77 | KMT2A (0.68) | MAPK10KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4066836 | 0.76 | KMT2A (0.67) | MAPK10KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10144692 | 0.76 | TSHR (0.78) | KDM4EKMT2ASMN1; SMN2MEN1TSHR | |
| SCHEMBL7398052 | 0.76 | KMT2A (1.00) | MAPK10KDM4EKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000030646-A1 | HETEROCYCLIC COMPOUNDS REGULATING CLOTTING | NOVO NORDISK A/S (DK) | 2000-06-02 | — | — | WO | disclosed |