Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.78 |
| ▸ | NPC1 | O15118 | 2/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | APLNR | P35414 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17712451 | 0.92 | TSHR (0.83) | TSHRNPC1RAB9AKDM4ENPSR1 | |
| SCHEMBL17712450 | 0.84 | TSHR (0.69) | TSHRNPC1RAB9AKDM4ENPSR1 | |
| SCHEMBL29468637 | 0.81 | RAB9A (0.72) | TSHRNPC1RAB9AKDM4EAPLNR | |
| SCHEMBL26808965 | 0.78 | TSHR (0.76) | TSHRNPC1RAB9AKDM4EMAPT | |
| SCHEMBL28643816 | 0.78 | KDM4E (0.62) | TSHRNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL29684074 | 0.76 | TSHR (0.70) | TSHRNPC1RAB9AKDM4ENPSR1 | |
| SCHEMBL18737813 | 0.76 | SMN1; SMN2 (0.63) | TSHRNPC1KDM4EALDH1A1MAPT | |
| SCHEMBL7398166 | 0.76 | MAPK10 (0.69) | TSHRNPC1RAB9AKDM4ENPSR1 | |
| SCHEMBL7291904 | 0.76 | TSHR (0.74) | TSHRNPC1RAB9AAPLNRALDH1A1 | |
| SCHEMBL7991476 | 0.75 | MAPT (0.68) | TSHRNPC1RAB9ANPSR1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | TSHR 2802/4885NPC1 764/4885RAB9A 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.