Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10996751 | 0.84 | MAPT (0.53) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL28800245 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL9710536 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL11794354 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL9710538 | 0.79 | MAPT (0.55) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL24475548 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL2441292 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL4808027 | 0.78 | CES1 (0.56) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL521069 | 0.78 | MAPT (0.57) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL30912986 | 0.78 | DPP4 (0.45) | ALDH1A1MAPTHTTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230242-A1 | USE OF 9-SUBSTITUTED HYPOXANTHINE DERIVATIVES TO STIMULATE REGENERATION OF NERVOUS TISSUE | Neotherapeutics, Inc. (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036419-A9 | USE OF 9-SUBSTITUTED HYPOXANTHINE DERIVATIVES TO STIMULATE REGENERATION OF NERVOUS TISSUE | NEOTHERAPEUTICS INC (US) | 2002-08-08 | — | — | WO | disclosed |
| US-6288069-B1 | Use of 9-substituted hypoxanthine derivatives to stimulate regeneration of nervous tissue | NEOTHERAPEUTICS, INC. | 2001-09-11 | — | — | US | disclosed |
| WO-2001036419-A1 | USE OF 9-SUBSTITUTED HYPOXANTHINE DERIVATIVES TO STIMULATE REGENERATION OF NERVOUS TISSUE | NEOTHERAPEUTICS, INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| EP-0522082-B1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | GLASKY ALVIN J (US) | 1997-07-02 | — | — | EP | disclosed |
| EP-0522082-A4 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | — | 1993-06-09 | — | — | EP | disclosed |
| EP-0522082-A1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE. | GLASKY ALVIN J (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5091432-A | Synergistic | SPECTRUM PHARMACEUTICALS, INC. | 1992-02-25 | — | — | US | disclosed |
| WO-1991014434-A1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | GLASKY ALVIN J (US) | 1991-10-03 | — | — | WO | disclosed |