Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16396156 | 0.90 | ACP3 (0.59) | TP53ACP3L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL17064382 | 0.81 | ACP3 (0.49) | ACP3L3MBTL1SMN1; SMN2HTTLMNA | |
| SCHEMBL7805676 | 0.78 | TSHR (0.48) | ACP3L3MBTL1SMN1; SMN2LMNAHPGD | |
| SCHEMBL7229711 | 0.77 | KMT2A (0.54) | ACP3L3MBTL1SMN1; SMN2HTTLMNA | |
| SCHEMBL7402172 | 0.76 | L3MBTL1 (0.51) | TP53ACP3L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL9154689 | 0.75 | L3MBTL1 (0.62) | TP53ACP3L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL16951631 | 0.75 | TSHR (0.53) | TP53ACP3L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL2234292 | 0.75 | L3MBTL1 (0.62) | TP53ACP3L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL31376571 | 0.75 | L3MBTL1 (0.62) | TP53ACP3L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL15617595 | 0.75 | CNR1 (0.56) | L3MBTL1SMN1; SMN2LMNAHPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623126-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014081-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-07-22 | — | — | WO | disclosed |