Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 10/20 | 0.54 |
| ▸ | MMP1 | P03956 | 3/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | CPA2 | P48052 | 1/20 | 0.48 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 2/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399623 | 0.92 | MMP3 (0.60) | MMP3MMP1CPA1CPA2CPA4 | |
| SCHEMBL7391699 | 0.86 | MMP3 (0.69) | MMP3MMP1CPA1CPA2CPA4 | |
| SCHEMBL8858199 | 0.85 | MMP3 (0.54) | MMP3MMP1CPA1CPA2CPA4 | |
| SCHEMBL7374189 | 0.68 | MMP3 (0.52) | MMP3MMP1CPA1CPA2CPA4 | |
| SCHEMBL6203155 | 0.65 | MMP3 (0.75) | MMP3MMP1CPA1CPA2CPA4 | |
| SCHEMBL11765572 | 0.65 | MMP3 (0.58) | MMP3MMP1CPA1CPA2CPA4 | |
| SCHEMBL11765562 | 0.65 | MMP3 (0.58) | MMP3MMP1CPA1CPA2CPA4 | |
| SCHEMBL7401167 | 0.63 | MMP3 (0.58) | MMP3MMP1CPA1CPA2CPA4 | |
| SCHEMBL7401165 | 0.63 | MMP3 (0.58) | MMP3MMP1CPA1CPA2CPA4 | |
| SCHEMBL8104234 | 0.63 | POLB (0.65) | CPA1CPA2CPA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623143-A1 | SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS | MERCK & CO. INC. (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014112-A1 | SUBSTITUTED PHOSPHINIC ACID-CONTAINING PEPTIDYL DERIVATIVES AS ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1993-07-22 | — | — | WO | disclosed |