Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4517509 | 0.87 | GAA (0.51) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL4507930 | 0.83 | GAA (0.47) | GAANFKB1NFKB2RELAPLG | |
| SCHEMBL23282460 | 0.82 | GAA (0.55) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL22728463 | 0.82 | GAA (0.55) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL8837694 | 0.77 | GAA (0.52) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL22482787 | 0.77 | GAA (0.52) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL22482790 | 0.77 | GAA (0.52) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL8837689 | 0.77 | GAA (0.52) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL4985702 | 0.77 | GAA (0.52) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL29675327 | 0.77 | GAA (0.52) | GAABTKNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000055156-A1 | SUBSTITUTED AROMATIC AMIDINE DERIVATIVE AND MEDICINAL COMPOSITION COMPRISING THE SAME | C & C RESEARCH LABORATORIES (KR) | 2000-09-21 | — | — | WO | disclosed |