Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.57 |
| ▸ | F13A1 | P00488 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | BID | P55957 | 4/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795917 | 0.93 | IAPP (0.61) | IAPPBIDMCL1BCL2L1BAK1 | |
| Palmitic Acid SCHEMBL27612750 | 0.86 | IAPP (0.62) | IAPPMAPTBIDMCL1BCL2L1 | |
| SCHEMBL17078356 | 0.86 | MAPT (0.61) | IAPPF13A1MAPTRXFP1BID | |
| SCHEMBL8009468 | 0.86 | MAPT (0.61) | IAPPF13A1MAPTRXFP1BID | |
| SCHEMBL2517305 | 0.86 | MAPT (0.61) | IAPPF13A1MAPTRXFP1BID | |
| SCHEMBL17078364 | 0.86 | MAPT (0.61) | IAPPF13A1MAPTRXFP1BID | |
| SCHEMBL16230472 | 0.86 | MAPT (0.61) | IAPPF13A1MAPTRXFP1BID | |
| SCHEMBL244943 | 0.85 | IAPP (0.70) | IAPP | |
| SCHEMBL30485631 | 0.85 | IAPP (0.70) | IAPP | |
| SCHEMBL31086218 | 0.85 | F13A1 (0.51) | F13A1MAPTRXFP1BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646183-A | Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5612355-A | Phenyl amidine lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |