SCHEMBL244943

SCHEMBL244943

O=C(O)CCc1cccc(O)c1O

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IAPP P10997 4/20 0.70
AKR1B1 P15121 1/20 0.50
PTGER1 P34995 1/20 0.49
PTGER4 P35408 1/20 0.49
PTGER3 P43115 1/20 0.49
PTGER2 P43116 1/20 0.49
KEAP1 Q14145 1/20 0.47
PARP1 P09874 1/20 0.46
POLB P06746 1/20 0.45
HMGB1 P09429 1/20 0.44
FFAR1 O14842 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30485631 1.00 IAPP (0.70) IAPPAKR1B1PTGER1PTGER4PTGER3
Ammonia Solution, Strong SCHEMBL31621217 0.98 IAPP (0.68) IAPPAKR1B1PTGER1PTGER4PTGER3
Phenyl Propionic Acid SCHEMBL5073243 0.91 KEAP1 (0.63) IAPPAKR1B1PTGER1PTGER4PTGER3
SCHEMBL16795917 0.89 IAPP (0.61) IAPPAKR1B1
SCHEMBL7399102 0.85 IAPP (0.57) IAPP
SCHEMBL7128255 0.83 AKR1B1 (0.65) IAPPAKR1B1PTGER1PTGER4PTGER3
SCHEMBL29373796 0.83 AKR1B1 (0.65) IAPPAKR1B1PTGER1PTGER4PTGER3
SCHEMBL35529 0.83 AKR1B1 (0.65) IAPPAKR1B1PTGER1PTGER4PTGER3
SCHEMBL30203505 0.82 IAPP (0.68) IAPPAKR1B1HMGB1NPSR1
SCHEMBL31086284 0.82 IAPP (0.49) IAPPAKR1B1PTGER1PTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118925514-A Separation membrane based on metal organic framework, preparation method thereof and lithium extraction device 广东邦普循环科技有限公司 2024-11-12 CN claimed
CN-118688333-A Marker related to allergic rhinitis and kit thereof 厦门市迈理奥科技有限公司 2024-09-24 CN claimed
US-20230272232-A1 Low Temperature Antioxidant Reductant for Copper Nanoparticles NNSA 2023-08-31 US claimed
EP-4206236-A1 COMPOUNDS, THEIR SYNTHESIS AND COMPOSITIONS COMPRISING THE COMPOUNDS FOR ENHANCED DEPOSITION OF POLYMERS ONTO HAIR SURFACES Kao Corporation (JP) 2023-07-05 EP claimed
CN-114177359-B Antibacterial coating and preparation method and application thereof 广东省科学院健康医学研究所 2023-03-24 CN claimed
US-11564877-B2 Responsive coatings for hair fibers L'OREAL (FR) 2023-01-31 US claimed
CN-112210091-B Multifunctional natural polysaccharide repairing adhesive hydrogel, preparation method and application of multifunctional natural polysaccharide repairing adhesive hydrogel in preparation of medicines for treating skin injury 吉林大学 2021-08-10 CN claimed
CN-112451735-A Epsilon-polylysine-based mussel-like coordination adhesive and preparation method thereof 天津大学 2021-03-09 CN claimed
CN-112210091-A Multifunctional natural polysaccharide repairing adhesive hydrogel, preparation method and application of multifunctional natural polysaccharide repairing adhesive hydrogel in preparation of medicines for treating skin injury 吉林大学 2021-01-12 CN claimed
US-20200113809-A1 RESPONSIVE COATINGS FOR HAIR FIBERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2020-04-16 US claimed
EP-2334305-A1 BIOADHESIVE CONSTRUCTS KNC NER Acquisition Sub, Inc. (US) 2011-06-22 EP claimed
WO-2011002995-A1 PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHODS OF MAKING AND USE THEREOF KEMPHARM, INC. (US) 2011-01-06 WO claimed
US-20110002991-A1 PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHOD OF MAKING AND USE THEREOF ALTER DOMUS (US) LLC 2011-01-06 US claimed
WO-2010037044-A1 BIOADHESIVE CONSTRUCTS NERITES CORPORATION (US) 2010-04-01 WO claimed
WO-2010037045-A1 MULTI-ARMED CATECHOL COMPOUND BLENDS NERITES CORPORATION (US) 2010-04-01 WO claimed
US-20090130739-A1 Deactivation of mineral encapsulated nanobacteria AMERICAN STERILIZER COMPANY (US) 2009-05-21 US claimed
WO-2006010246-A1 THE ISOLATION AND CHARACTERIZATION OF A GENE ENCODING A LITTORINE MUTASE/HYDROXYLASE, TRANSGENIC PLANTS AND USES THEREOF FOR ALERTING ALKALOID BIOSYNTHESIS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2006-02-02 WO claimed
JP-2002524505-A 2002-08-06 JP claimed
EP-1113790-A1 COMPOSITION CONTAINING CINNAMIC ACID DERIVATIVES FOR PREVENTING OR TREATING ELEVATED BLOOD LIPID LEVEL-RELATED DISEASES Korea Research Institute of Bioscience and Biotechnology (KR) 2001-07-11 EP claimed
WO-2000015215-A1 COMPOSITION CONTAINING CINNAMIC ACID DERIVATIVES FOR PREVENTING OR TREATING ELEVATED BLOOD LIPID LEVEL-RELATED DISEASES KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2000-03-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11564877-B2 Responsive coatings for hair fibers KRT18, PLOD3, PLOD1 IAPP 4653/4885AKR1B1 1990/4885PTGER1 3289/4885
US-20110002991-A1 PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHOD OF MAKING AND USE THEREOF CYP7A1, CYP2B6, CYP2D6 IAPP 3796/4885AKR1B1 840/4885PTGER1 127/4885
US-20200113809-A1 RESPONSIVE COATINGS FOR HAIR FIBERS KRT18, PLOD3, PLOD1 IAPP 4653/4885AKR1B1 1990/4885PTGER1 3289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.