Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 14/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 14/20 | 1.00 |
| ▸ | CHRM4 | P08173 | 13/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 13/20 | 1.00 |
| ▸ | CHRM3 | P20309 | 13/20 | 1.00 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9431490 | 0.73 | CHRM2 (0.65) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL8988269 | 0.63 | CHRM2 (0.55) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9431395 | 0.62 | FDFT1 (0.56) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL9432175 | 0.62 | FDFT1 (0.55) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL9342898 | 0.60 | CHRM2 (0.49) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9910975 | 0.59 | QDPR (0.47) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL4691052 | 0.59 | CHRM2 (1.00) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL9431085 | 0.59 | CHRM2 (0.97) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL27989815 | 0.59 | CYP2A6 (0.74) | — | |
| SCHEMBL4688368 | 0.58 | CHRM2 (1.00) | CHRM2CHRM1CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640082-A1 | HETEROAROMATIC QUINUCLIDINENES, THEIR USE AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1995-03-01 | — | — | EP | claimed |
| WO-1993023395-A1 | HETEROAROMATIC QUINUCLIDINENES, THEIR USE AND PREPARATION | KABI PHARMACIA AB (SE) | 1993-11-25 | — | — | WO | claimed |
| US-5599937-A | Heteroaromatic quinuclidinenes, their use and preparation | PHARMACIA AB (SE) | 1997-02-04 | — | — | US | disclosed |
| EP-0640082-A1 | HETEROAROMATIC QUINUCLIDINENES, THEIR USE AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1995-03-01 | — | — | EP | disclosed |
| WO-1993023395-A1 | HETEROAROMATIC QUINUCLIDINENES, THEIR USE AND PREPARATION | KABI PHARMACIA AB (SE) | 1993-11-25 | — | — | WO | disclosed |