Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.60 |
| ▸ | CTSB | P07858 | 7/20 | 0.58 |
| ▸ | CTSK | P43235 | 5/20 | 0.58 |
| ▸ | CTSS | P25774 | 4/20 | 0.58 |
| ▸ | CTSH | P09668 | 2/20 | 0.58 |
| ▸ | CTSC | P53634 | 2/20 | 0.58 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361758 | 1.00 | CTSL (0.60) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL7356643 | 0.87 | CTSL (0.61) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL7356648 | 0.87 | CTSL (0.61) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL7362787 | 0.87 | CTSL (0.61) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL7356627 | 0.87 | CTSL (0.61) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL7362789 | 0.87 | CTSL (0.61) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL7362782 | 0.87 | CTSL (0.61) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL7354429 | 0.81 | CTSL (0.59) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL7354419 | 0.81 | CTSL (0.59) | CTSLCTSBCTSKCTSSCTSH | |
| SCHEMBL7354432 | 0.81 | CTSL (0.59) | CTSLCTSBCTSKCTSSCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756625-A4 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | ARRIS PHARM CORP (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0756625-A1 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-02-05 | — | — | EP | disclosed |
| WO-1995023222-A1 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | KHEPRI PHARMACEUTICALS, INC. (US) | 1995-08-31 | — | — | WO | disclosed |