Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.36 |
| ▸ | ITGAV | P06756 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 4/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419041 | 0.92 | ITGB3 (0.37) | ITGB3ITGA2BITGAVMAPTGALR3 | |
| SCHEMBL7407629 | 0.92 | ITGB3 (0.37) | ITGB3ITGA2BITGAVMMP8MMP3 | |
| SCHEMBL7398477 | 0.84 | ITGB3 (0.44) | ITGB3ITGA2BITGAV | |
| SCHEMBL6419328 | 0.84 | ITGB3 (0.38) | ITGB3ITGA2BITGAV | |
| SCHEMBL6419321 | 0.83 | ITGB3 (0.38) | ITGB3ITGA2BITGAV | |
| SCHEMBL6788739 | 0.83 | ITGB3 (0.40) | ITGB3ITGA2BITGAV | |
| SCHEMBL6418120 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BITGAV | |
| SCHEMBL6419279 | 0.79 | ITGB3 (0.45) | ITGB3ITGA2BITGAV | |
| SCHEMBL6418659 | 0.77 | ITGB3 (0.43) | ITGB3ITGA2BITGAV | |
| SCHEMBL7399466 | 0.77 | ITGB3 (0.44) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957917-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-05-15 | — | — | EP | disclosed |
| EP-0957917-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998014192-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-09 | — | — | WO | disclosed |