Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948613 | 0.79 | KDM4C (0.40) | KDM4CL3MBTL1NPC1RAB9ATGFBR1 | |
| SCHEMBL6950944 | 0.71 | KDM4C (0.41) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL6948526 | 0.71 | KDM4C (0.40) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL6950695 | 0.69 | KDM4C (0.38) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL22468349 | 0.67 | KDM4C (0.40) | KDM4CL3MBTL1NPC1RAB9APDE10A | |
| SCHEMBL29356162 | 0.67 | KDM4C (0.40) | KDM4CL3MBTL1NPC1RAB9APDE10A | |
| SCHEMBL6957600 | 0.67 | KDM4C (0.39) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL10683875 | 0.66 | MEN1 (0.57) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL6953035 | 0.66 | KDM4C (0.40) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL10683252 | 0.65 | MEN1 (0.47) | KDM4CL3MBTL1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074549-A2 | Tetrahydro-benzo(d)azepines and their use as antagonists at metabotropic glutamate receptors | F. HOFFMANN-LA ROCHE AG (CH) | 2001-02-07 | — | — | EP | disclosed |