Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605526 | 0.80 | ADORA2A (0.50) | ADORA2AADORA2BLMNARECQLKMT2A | |
| SCHEMBL6606918 | 0.76 | LMNA (0.41) | ADORA2AADORA2BLMNARECQLKMT2A | |
| SCHEMBL3805543 | 0.68 | AOC3 (0.39) | KMT2AMEN1CA2 | |
| SCHEMBL25062632 | 0.68 | CYP2A6 (0.57) | ADORA2AADORA2BLMNARECQLKMT2A | |
| SCHEMBL10963586 | 0.67 | KMT2A (0.54) | ADORA2AADORA2BLMNARECQLKMT2A | |
| SCHEMBL11303560 | 0.66 | LMNA (0.54) | ADORA2AADORA2BLMNARECQLKMT2A | |
| SCHEMBL21788603 | 0.65 | KMT2A (0.55) | ADORA2AADORA2BLMNARECQLKMT2A | |
| SCHEMBL29793869 | 0.65 | KMT2A (0.55) | ADORA2AADORA2BLMNARECQLKMT2A | |
| SCHEMBL73352 | 0.65 | LMNA (0.56) | ADORA2AADORA2BLMNARECQLKMT2A | |
| SCHEMBL11346198 | 0.65 | LMNA (0.53) | ADORA2AADORA2BLMNARECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257548-A1 | BENZOFURAN CARBOXAMIDES AND THEIR THERAPEUTIC USE | Darwin Discovery Limited (GB) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001058895-A1 | BENZOFURAN CARBOXAMIDES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LIMITED (GB) | 2001-08-16 | — | — | WO | disclosed |