Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.69 |
| ▸ | CTSL | P07711 | 3/20 | 0.61 |
| ▸ | CTSB | P07858 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389651 | 0.84 | CTSS (0.79) | CTSS | |
| SCHEMBL6797373 | 0.81 | CTSS (0.74) | CTSS | |
| SCHEMBL7032794 | 0.80 | CTSS (1.00) | CTSS | |
| SCHEMBL6795452 | 0.80 | CTSS (0.81) | CTSS | |
| SCHEMBL7395741 | 0.78 | CTSS (0.77) | CTSS | |
| SCHEMBL6802014 | 0.78 | CTSS (0.81) | CTSS | |
| SCHEMBL5523884 | 0.78 | CTSS (0.73) | CTSSCTSLCTSB | |
| SCHEMBL7393092 | 0.77 | CTSS (1.00) | CTSSCTSL | |
| SCHEMBL7397903 | 0.76 | CTSS (0.84) | CTSS | |
| SCHEMBL7240074 | 0.76 | CTSS (1.00) | CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002538151-A | — | — | 2002-11-12 | — | — | JP | claimed |
| EP-1159273-A1 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CATHEPSIN S | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2001-12-05 | — | — | EP | claimed |
| WO-2000051998-A1 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CATHEPSIN S | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-09-08 | — | — | WO | claimed |