Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405015 | 0.91 | ADAM17 (0.64) | ADAM17MMP13 | |
| SCHEMBL7403315 | 0.89 | ADAM17 (0.74) | ADAM17MMP13 | |
| SCHEMBL7401790 | 0.87 | ADAM17 (0.62) | ADAM17MMP13 | |
| SCHEMBL7407469 | 0.87 | ADAM17 (0.76) | ADAM17MMP13 | |
| SCHEMBL6598612 | 0.87 | ADAM17 (0.83) | ADAM17MMP13 | |
| SCHEMBL7395828 | 0.86 | ADAM17 (0.58) | ADAM17MMP13 | |
| SCHEMBL7399912 | 0.86 | ADAM17 (0.73) | ADAM17MMP13 | |
| SCHEMBL7401098 | 0.86 | ADAM17 (0.61) | ADAM17MMP13 | |
| SCHEMBL7402156 | 0.86 | ADAM17 (0.75) | ADAM17MMP13 | |
| SCHEMBL7509448 | 0.86 | ADAM17 (0.65) | ADAM17MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263756-A2 | BETA-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-ALPHA | Bristol-Myers Squibb Pharma Company (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001070734-A2 | BETA-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-ALPHA | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |