Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14371962 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HPGDSMN1; SMN2LMNAGRM5 | |
| SCHEMBL4088050 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HPGDSMN1; SMN2LMNAGRM5 | |
| SCHEMBL8893000 | 0.80 | CYP3A4 (0.55) | ALDH1A1HPGDSMN1; SMN2LMNAGRM5 | |
| SCHEMBL3505447 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNAGRM5CTSA | |
| SCHEMBL10708175 | 0.79 | ALDH1A1 (0.66) | ALDH1A1HPGDLMNAGRM5CTSA | |
| SCHEMBL1037003 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HPGDSMN1; SMN2LMNAGRM5 | |
| SCHEMBL31055457 | 0.78 | HPGD (0.57) | ALDH1A1HPGDSMN1; SMN2LMNAGRM5 | |
| SCHEMBL6931 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HPGDLMNAGRM5 | |
| SCHEMBL24150763 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HPGDLMNAGRM5CTSA | |
| Hydrochloric Acid SCHEMBL10707808 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HPGDLMNAGRM5CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |