Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399993 | 1.00 | ADORA2B (0.62) | ADORA2B | |
| SCHEMBL7400082 | 0.85 | — | — | |
| SCHEMBL7400086 | 0.85 | — | — | |
| SCHEMBL7397100 | 0.83 | ADORA2B (0.62) | ADORA2B | |
| SCHEMBL7397099 | 0.83 | ADORA2B (0.62) | ADORA2B | |
| SCHEMBL7313322 | 0.80 | KDM4E (0.48) | ADORA2B | |
| SCHEMBL7313333 | 0.80 | KDM4E (0.48) | ADORA2B | |
| SCHEMBL7401160 | 0.78 | — | — | |
| SCHEMBL7401162 | 0.78 | — | — | |
| SCHEMBL516344 | 0.77 | ADORA2B (1.00) | ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861405-A | A2-SELECTIVE ADENOSINE RECEPTOR ANTAGONIST AS ANTIDEPRESSANTS AND CNS STIMULANTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-01-19 | — | — | US | disclosed |
| WO-1994025462-A1 | 8-SUBSTITUTED 1,3,7-TRIALKYL-XANTHINE DERIVATIVES AS A2-SELECTIVE ADENOSINE RECEPTOR ANTAGONISTS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE (US) | 1994-11-10 | — | — | WO | disclosed |