Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 6/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1518735 | 0.94 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2424312 | 0.93 | MAPK9 (0.55) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2420821 | 0.88 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2425499 | 0.87 | MAPK9 (0.55) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2420483 | 0.85 | MAPK9 (0.55) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL4189441 | 0.84 | MAPK9 (0.57) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2421312 | 0.84 | MAPK9 (0.57) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2422729 | 0.84 | MAPK9 (0.57) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2422241 | 0.84 | MEN1 (0.49) | MAPK9MAPK10MEN1KMT2AMAPT | |
| SCHEMBL2422037 | 0.84 | MAPK9 (0.59) | MAPK9MAPK10MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |