Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637777 | 0.94 | ELANE (0.42) | FCER2ELANECNR1CNR2ITGB1 | |
| SCHEMBL7644394 | 0.90 | SYK (0.37) | CNR1CNR2 | |
| SCHEMBL7643027 | 0.85 | ACE (0.38) | CNR1CNR2ITGB1ITGA4 | |
| SCHEMBL7409905 | 0.80 | ACE (0.41) | PTPN1CNR1CNR2ITGB1ITGA4 | |
| SCHEMBL7408062 | 0.77 | XIAP (0.37) | — | |
| SCHEMBL7642932 | 0.73 | XIAP (0.34) | — | |
| SCHEMBL7400637 | 0.72 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL7644396 | 0.71 | XIAP (0.43) | — | |
| SCHEMBL7640967 | 0.71 | ATM (0.47) | MMP1ELANE | |
| SCHEMBL7288109 | 0.69 | ACE (0.54) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001090095-A1 | THIADIAZOLE COMPOUNDS USEFUL AS INHIBITORS OF CYSTEINE ACTIVITY DEPENDENT ENZYMES | APOTEX INC. (CA) | 2001-11-29 | — | — | WO | disclosed |