Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 9/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408062 | 0.85 | XIAP (0.37) | FPR2SCN9AL3MBTL1XIAPSMN1; SMN2 | |
| SCHEMBL7637777 | 0.82 | ELANE (0.42) | CNR2CNR1 | |
| SCHEMBL7642932 | 0.81 | XIAP (0.34) | L3MBTL1XIAPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7400637 | 0.80 | SMN1; SMN2 (0.33) | L3MBTL1XIAPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7644396 | 0.79 | XIAP (0.43) | XIAPSMN1; SMN2LMNA | |
| SCHEMBL7447829 | 0.77 | ACE (0.46) | L3MBTL1LMNA | |
| SCHEMBL7408066 | 0.76 | XIAP (0.55) | L3MBTL1XIAPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7406241 | 0.75 | L3MBTL1 (0.36) | L3MBTL1XIAPSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7403583 | 0.74 | L3MBTL1 (0.36) | L3MBTL1XIAPSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7403586 | 0.72 | RAB9A (0.41) | L3MBTL1XIAPSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468977-B1 | COMPOUNDS USEFUL IN TREATMENT TREATMENT OF DISORDER AND/OR DISEASE CAUSED BY ACTIVITY OF ENZYMES SUCH AS HUMAN RHINOVIRUS 3C PROTEASE, TRANSGLUTAMINASE AND CATHEPSINS | APOTEX INC. (CA) | 2002-10-22 | — | — | US | disclosed |