Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405208 | 0.89 | GPR119 (0.52) | GPR119KDM4EPKMSCN9ACHEK2 | |
| SCHEMBL31752872 | 0.88 | CHEK2 (0.56) | GPR119KDM4EPKMSCN9ACHEK2 | |
| SCHEMBL14426349 | 0.85 | GPR119 (0.51) | GPR119KDM4EPKMSCN9ACHEK2 | |
| SCHEMBL7402974 | 0.85 | GPR119 (0.64) | GPR119KDM4EPKMCHEK2MAPT | |
| SCHEMBL10296175 | 0.84 | GPR119 (0.56) | GPR119KDM4EPKMFAAHMAPT | |
| SCHEMBL7401143 | 0.84 | GPR119 (0.62) | GPR119TP53MAPTTHRB | |
| SCHEMBL1575509 | 0.82 | KDM4E (0.51) | GPR119KDM4EPKMFAAH | |
| SCHEMBL1575876 | 0.82 | GPR119 (0.53) | GPR119KDM4EPKMSCN9AFAAH | |
| SCHEMBL7403698 | 0.82 | SCN9A (0.51) | GPR119KDM4EPKMSCN9ACHEK2 | |
| SCHEMBL1575979 | 0.82 | GPR119 (0.53) | GPR119KDM4EPKMFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |