Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 20/20 | 1.00 |
| ▸ | CHRM4 | P08173 | 20/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 20/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 20/20 | 1.00 |
| ▸ | CHRM3 | P20309 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400441 | 0.75 | CHRM2 (0.60) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4692117 | 0.56 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7392899 | 0.55 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7397203 | 0.54 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL31038060 | 0.53 | TTR (0.64) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7401282 | 0.52 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9451873 | 0.51 | CA12 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL22197816 | 0.50 | TTR (0.58) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Ioxynil SCHEMBL1701373 | 0.50 | TTR (1.00) | — | |
| SCHEMBL11209099 | 0.50 | TTR (0.58) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599937-A | Heteroaromatic quinuclidinenes, their use and preparation | PHARMACIA AB (SE) | 1997-02-04 | — | — | US | disclosed |
| EP-0640082-A1 | HETEROAROMATIC QUINUCLIDINENES, THEIR USE AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1995-03-01 | — | — | EP | disclosed |
| WO-1993023395-A1 | HETEROAROMATIC QUINUCLIDINENES, THEIR USE AND PREPARATION | KABI PHARMACIA AB (SE) | 1993-11-25 | — | — | WO | disclosed |