Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.54 |
| ▸ | HTR2C | P28335 | 13/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.49 |
| ▸ | HTR3B | O95264 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298474 | 0.74 | HTR1A (0.57) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL7305667 | 0.70 | HTR1A (1.00) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL20674153 | 0.68 | BAZ2B (0.41) | — | |
| SCHEMBL7305847 | 0.66 | HTR1A (0.67) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL7299090 | 0.66 | HTR1A (1.00) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL21959620 | 0.66 | KDM4E (0.40) | — | |
| SCHEMBL7309256 | 0.66 | HTR1A (0.56) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL7302550 | 0.65 | HTR1A (0.70) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL7297117 | 0.65 | HTR1A (0.80) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL7293903 | 0.64 | HTR1A (1.00) | HTR1AHTR2CHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014381-A1 | ETHER DERIVATIVES OF PYRROLO[1,2-A]QUINOXALINES, METHOD FOR PRODUCING THEM AND THEIR USE IN THERAPY | UNIVERSITE DE CAEN BASSE-NORMANDIE (FR) | 2001-03-01 | — | — | WO | disclosed |