Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400528 | 1.00 | ATM (0.41) | ATMSIGMAR1GRIN2BPKMMEN1 | |
| SCHEMBL7400530 | 1.00 | ATM (0.41) | ATMSIGMAR1GRIN2BPKMMEN1 | |
| SCHEMBL7396300 | 0.84 | ALDH1A1 (0.39) | SIGMAR1MEN1KMT2A | |
| SCHEMBL7396296 | 0.84 | ALDH1A1 (0.39) | SIGMAR1MEN1KMT2A | |
| SCHEMBL7396292 | 0.84 | ALDH1A1 (0.39) | SIGMAR1MEN1KMT2A | |
| SCHEMBL6942393 | 0.75 | CYP3A4 (0.46) | SIGMAR1GRIN2BMEN1KMT2ARAB9A | |
| SCHEMBL6942391 | 0.75 | CYP3A4 (0.46) | SIGMAR1GRIN2BMEN1KMT2ARAB9A | |
| SCHEMBL6942390 | 0.75 | CYP3A4 (0.46) | SIGMAR1GRIN2BMEN1KMT2ARAB9A | |
| SCHEMBL7401190 | 0.73 | MEN1 (0.44) | ATMSIGMAR1GRIN2BPKMMEN1 | |
| SCHEMBL7398866 | 0.70 | ATM (0.43) | ATMSIGMAR1GRIN2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |