Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7400578 | 0.98 | TKT (0.49) | TKTHSP90AA1 | |
| SCHEMBL5015373 | 0.98 | TKT (0.51) | TKTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL3849477 | 0.83 | TKT (0.51) | TKTHSP90AA1 | |
| Bromide SCHEMBL3844690 | 0.82 | TKT (0.45) | TKTHSP90AA1 | |
| Bromide SCHEMBL2946803 | 0.82 | TKT (0.46) | TKTHSP90AA1 | |
| Bromide SCHEMBL2955991 | 0.81 | TKT (0.57) | TKT | |
| Bromide SCHEMBL7820785 | 0.81 | TKT (0.44) | TKTHSP90AA1 | |
| SCHEMBL6936407 | 0.80 | TKT (0.46) | TKTHSP90AA1 | |
| Bromide SCHEMBL8941023 | 0.80 | TKT (0.54) | TKTHSP90AA1 | |
| SCHEMBL6937529 | 0.80 | TKT (0.58) | TKT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853703-A | Preventing and reversing the formation of advanced glycosylation endproducts | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1998-12-29 | — | — | US | claimed |
| EP-0808163-A2 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON, INC. (US) | 1997-11-26 | — | — | EP | claimed |
| WO-1996022095-A2 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC. (US) | 1996-07-25 | — | — | WO | claimed |