Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148163 | 1.00 | ATM (0.57) | ATMALDH1A1LDHAKMT2AGLA | |
| SCHEMBL7381205 | 1.00 | ATM (0.57) | ATMALDH1A1LDHAKMT2AGLA | |
| SCHEMBL5519612 | 0.86 | ATM (0.55) | ATMALDH1A1LDHAKMT2AGLA | |
| SCHEMBL5519606 | 0.86 | ATM (0.55) | ATMALDH1A1LDHAKMT2AGLA | |
| SCHEMBL4891761 | 0.86 | ATM (0.57) | ATMALDH1A1LDHAKMT2AGLA | |
| SCHEMBL4891760 | 0.86 | ATM (0.57) | ATMALDH1A1LDHAKMT2AGLA | |
| SCHEMBL11147827 | 0.84 | ATM (0.53) | ATMALDH1A1LDHAKMT2AGLA | |
| SCHEMBL3701587 | 0.84 | LMNA (0.58) | KMT2ALMNACA1CA2CTSL | |
| SCHEMBL2646824 | 0.84 | LMNA (0.58) | KMT2ALMNACA1CA2CTSL | |
| SCHEMBL2142734 | 0.84 | LMNA (0.58) | KMT2ALMNACA1CA2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219886-A | Cardiovascular disorders, analgesics, enzyme inhibitors | SCHERING CORPORATION (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0393441-B1 | MERCAPTO-ACYLAMINO ACIDS | SCHERING CORPORATION (US) | 1993-05-26 | — | — | EP | disclosed |
| EP-0467957-A1 | MERCAPTO-ACYLAMINO ACIDS | SCHERING CORPORATION (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0393441-A1 | Mercapto-acylamino acids | SCHERING CORPORATION (US) | 1990-10-24 | — | — | EP | disclosed |
| WO-1990012003-A1 | MERCAPTO-ACYLAMINO ACIDS | SCHERING CORPORATION (US) | 1990-10-18 | — | — | WO | disclosed |
| US-4296242-A | Process for the preparation of chiral 3-amino-2-hydroxypropionic acid and N-blocked derivatives thereof | SCHERING CORPORATION (US) | 1981-10-20 | — | — | US | disclosed |