Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910642 | 0.75 | DPP4 (0.36) | DPP4DPP7 | |
| SCHEMBL958997 | 0.75 | — | — | |
| SCHEMBL5482843 | 0.72 | DPP4 (0.40) | DPP4DPP7 | |
| SCHEMBL14270060 | 0.72 | DPP4 (0.40) | DPP4DPP7 | |
| SCHEMBL961221 | 0.70 | — | — | |
| SCHEMBL19401307 | 0.69 | DPP4 (0.33) | DPP4DPP7 | |
| SCHEMBL5678624 | 0.68 | DPP4 (0.33) | DPP4DPP7 | |
| SCHEMBL6587369 | 0.68 | — | — | |
| SCHEMBL6591795 | 0.68 | — | — | |
| SCHEMBL591395 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891331-A1 | N-(2 OXOACETYL OR SULPHONYL)-PYRROLIDINE/PIPERIDINE-2-CARBOXYLIC ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY | Vertex Pharmaceuticals Incorporated (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036869-A1 | N-(2 OXOACETYL OR SULPHONYL)-PYRROLIDINE/PIPERIDINE-2-CARBOXYLIC ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1997-10-09 | — | — | WO | disclosed |