SCHEMBL910642

SCHEMBL910642

COC1CCCC([C]=O)C1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.36
DPP7 Q9UHL4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921188 0.86
SCHEMBL750102 0.79
SCHEMBL5482843 0.75 DPP4 (0.40) DPP4DPP7
SCHEMBL14270060 0.75 DPP4 (0.40) DPP4DPP7
SCHEMBL7641265 0.75
SCHEMBL7400653 0.75 DPP4 (0.31) DPP4DPP7
SCHEMBL7289113 0.72 CHRM2 (0.42)
SCHEMBL19401307 0.72 DPP4 (0.33) DPP4DPP7
SCHEMBL910706 0.72 EPHX2 (0.30)
SCHEMBL22147939 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1590491-B1 ADDUCTS BASED ON CYCLIC COMPOUNDS AND THE USE THEREOF AS TANNING AGENTS AND CURING AGENTS BASF SE (DE) 2011-06-01 EP disclosed
US-20110004019-A1 Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same SHISEIDO COMPANY LTD. (JP) 2011-01-06 US disclosed
EP-2255780-A1 PARAKERATOSIS INHIBITOR, PORE SHRINKING AGENT OR AGENT FOR PREVENTING OR IMPROVING ROUGH SKIN, AND COMPOSITION FOR EXTERNAL USE ON THE SKIN CONTAINING THE SAME Shiseido Company, Ltd. (JP) 2010-12-01 EP disclosed
EP-1590492-B1 TANNING AGENTS AND PRESERVATIVES BASF SE (DE) 2009-04-15 EP disclosed
US-7410504-B2 Adducts based on cyclic compounds and the use thereof as tanning agents and curing agents BASF AKTIENGESELLSCHAFT (DE) 2008-08-12 US disclosed
US-7282066-B2 Processes for preparing and using tanning agents and preservatives BASF AKTIENGESELLSCHAFT (DE) 2007-10-16 US disclosed
US-20070101509-A1 Method for the production of leather and semifinished products, and formulations that are suitable therefor BASF AKIENGESELLSCHAFT (DE) 2007-05-10 US disclosed
EP-1670957-A1 METHOD FOR THE PRODUCTION OF LEATHER AND SEMIFINISHED PRODUCTS, AND FORMULATIONS THAT ARE SUITABLE THEREFOR BASF Aktiengesellschaft (DE) 2006-06-21 EP disclosed
US-20060101583-A1 Adducts based on cyclic compounds and the use thereof as tanning agents and curing agents BASF AKTIENGESELLSCHAFT (DE) 2006-05-18 US disclosed
US-20060053564-A1 Tanning agents and preservatives BASF AKTIENGESELLSCHAFT (DE) 2006-03-16 US disclosed
EP-1590491-A1 ADDUCTS BASED ON CYCLIC COMPOUNDS AND THE USE THEREOF AS TANNING AGENTS AND CURING AGENTS BASF Aktiengesellschaft (DE) 2005-11-02 EP disclosed
EP-1590492-A1 TANNING AGENTS AND PRESERVATIVES BASF AKTIENGESELLSCHAFT (DE) 2005-11-02 EP disclosed
WO-2005031007-A1 METHOD FOR THE PRODUCTION OF LEATHER AND SEMIFINISHED PRODUCTS, AND FORMULATIONS THAT ARE SUITABLE THEREFOR BASF AKTIENGESELLSCHAFT (DE) 2005-04-07 WO disclosed
WO-2004067781-A1 ADDUCTS BASED ON CYCLIC COMPOUNDS AND THE USE THEREOF AS TANNING AGENTS AND CURING AGENTS BASF AKTIENGESELLSCHAFT (DE) 2004-08-12 WO disclosed
WO-2004067782-A1 TANNING AGENTS AND PRESERVATIVES BASF AKTIENGESELLSCHAFT (DE) 2004-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110004019-A1 Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same CUTA, GLRA3, ARGLU1 DPP4 1370/4885DPP7 1832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.