Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.58 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363616 | 0.83 | HDAC3 (0.61) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7365575 | 0.74 | HDAC1 (1.00) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9003784 | 0.71 | HDAC3 (0.60) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL9487294 | 0.69 | HDAC1 (0.63) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7737575 | 0.67 | HDAC1 (0.69) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7496644 | 0.67 | HDAC1 (0.60) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4310754 | 0.66 | HDAC1 (0.56) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7739114 | 0.66 | HDAC1 (0.72) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| Acetic Acid SCHEMBL9000229 | 0.66 | RARB (0.72) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7738398 | 0.66 | HDAC1 (0.72) | HDAC1HDAC2HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002046129-A2 | INHIBITORS OF HISTONE DEACETYLASE | ABBOTT LABORATORIES (US) | 2002-06-13 | — | — | WO | disclosed |