Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.60 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003746 | 0.88 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6664687 | 0.82 | HDAC3 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7365575 | 0.76 | HDAC1 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7363616 | 0.76 | HDAC3 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9668080 | 0.73 | HRH3 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8379947 | 0.73 | HDAC3 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL351887 | 0.73 | ADRA2A (0.32) | — | |
| SCHEMBL7849175 | 0.72 | MAOA (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL381129 | 0.71 | ADRA2A (0.32) | — | |
| SCHEMBL10410293 | 0.71 | ADRA2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491201-A | HEAT/CHEMICAL RESISTANCE; HIGH MECHANICAL STRENGTH | THE DOW CHEMICAL COMPANY (US) | 1996-02-13 | — | — | US | claimed |
| US-5338828-A | Mesogenic cyclic imino ether-containing compositions and polymerization products thereof | THE DOW CHEMICAL COMPANY (US) | 1994-08-16 | — | — | US | claimed |
| US-5491201-A | HEAT/CHEMICAL RESISTANCE; HIGH MECHANICAL STRENGTH | THE DOW CHEMICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| US-5338828-A | Mesogenic cyclic imino ether-containing compositions and polymerization products thereof | THE DOW CHEMICAL COMPANY (US) | 1994-08-16 | — | — | US | disclosed |