Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.93 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.62 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SCN4A | P35499 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768488 | 1.00 | ALOX15 (0.93) | ALOX15KDM4ECYP1A2KMT2ALMNA | |
| SCHEMBL768489 | 1.00 | ALOX15 (0.93) | ALOX15KDM4ECYP1A2KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL11100810 | 0.98 | ALOX15 (0.97) | ALOX15KDM4ECYP1A2KMT2ALMNA | |
| SCHEMBL18423672 | 0.89 | KDM4E (0.82) | ALOX15KDM4ECYP1A2KMT2ALMNA | |
| SCHEMBL772845 | 0.86 | ALOX15 (0.71) | ALOX15KDM4ECYP1A2KMT2ALMNA | |
| SCHEMBL13889769 | 0.86 | ALOX15 (0.71) | ALOX15KDM4ECYP1A2KMT2ALMNA | |
| SCHEMBL9720877 | 0.84 | ALOX15 (0.69) | ALOX15KDM4ECYP1A2KMT2ALMNA | |
| Mephenesin SCHEMBL6482337 | 0.84 | CYP1A2 (1.00) | ALOX15KDM4ECYP1A2KMT2ALMNA | |
| Mephenesin SCHEMBL25448 | 0.84 | CYP1A2 (1.00) | ALOX15KDM4ECYP1A2KMT2ALMNA | |
| Mephenesin SCHEMBL332864 | 0.84 | CYP1A2 (1.00) | ALOX15KDM4ECYP1A2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741705-A1 | 4-(2-(3-ARYLOXY-2-HYDROXYPROPYLAMINO ALKYLOXY)-5-NITROPHENYL)-1,4-DIHYDROPYRIDINES AS ANTIHYPERTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020576-A1 | 4-(2-(3-ARYLOXY-2-HYDROXYPROPYLAMINO ALKYLOXY)-5-NITROPHENYL)-1,4-DIHYDROPYRIDINES AS ANTIHYPERTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-03 | — | — | WO | disclosed |