Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277628 | 0.88 | HRH3 (0.46) | ITGB3ITGA2BHRH3ACACBHRH1 | |
| SCHEMBL8603764 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BHRH3ACACBHRH1 | |
| SCHEMBL7334548 | 0.85 | ITGB3 (0.62) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7402483 | 0.84 | ITGB3 (0.44) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7396532 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL8890373 | 0.81 | ITGB3 (0.60) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL27462632 | 0.77 | HRH3 (0.44) | HRH3ACACBHRH1GSK3BHRH2 | |
| SCHEMBL7335391 | 0.76 | HRH3 (0.50) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL27930045 | 0.75 | MAPT (0.53) | GSK3BMAPT | |
| Hydrochloric Acid SCHEMBL8634754 | 0.74 | GSK3B (0.45) | GSK3BCYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |