Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.54 |
| ▸ | HRH1 | P35367 | 4/20 | 0.51 |
| ▸ | HRH2 | P25021 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630665 | 0.84 | HRH3 (0.49) | HRH3HRH1HRH2HTR1ADRD2 | |
| SCHEMBL7494779 | 0.82 | HRH3 (0.50) | HRH3HRH1HRH2HTR1ADRD2 | |
| SCHEMBL7402486 | 0.81 | HRH3 (0.48) | HRH3HRH1HRH2HTR1ADRD2 | |
| SCHEMBL7396534 | 0.80 | HRH3 (0.48) | HRH3HRH1HRH2HTR1ADRD2 | |
| SCHEMBL8630604 | 0.75 | CYP2C9 (0.43) | HRH3HRH1HRH2 | |
| SCHEMBL8635833 | 0.74 | CYP2C9 (0.45) | HRH3HRH1HRH2 | |
| SCHEMBL7397664 | 0.74 | ITGB3 (0.57) | HRH3HRH1 | |
| SCHEMBL15392656 | 0.74 | KDM4E (0.50) | — | |
| Hydrochloric Acid SCHEMBL8681089 | 0.74 | CYP2C9 (0.44) | HRH3HRH1HRH2 | |
| Hydrochloric Acid SCHEMBL8637474 | 0.74 | CYP2C9 (0.44) | HRH3HRH1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |