Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.71 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.70 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | CASP4 | P49662 | 1/20 | 0.63 |
| ▸ | CASP5 | P51878 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | CASP9 | P55211 | 1/20 | 0.63 |
| ▸ | CASP6 | P55212 | 1/20 | 0.63 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.63 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.63 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 3/20 | 0.51 |
| ▸ | CCKBR | P32239 | 3/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069771 | 0.94 | MAGI3 (0.77) | EDNRAMAGI3CASP1CASP3CASP4 | |
| SCHEMBL7400880 | 0.92 | EDNRA (0.69) | EDNRAMAGI3CASP1CASP3CASP4 | |
| SCHEMBL30533185 | 0.92 | EDNRA (0.82) | EDNRAMAGI3CASP1CASP3CASP4 | |
| SCHEMBL7395342 | 0.91 | EDNRA (0.81) | EDNRAMAGI3ERAP2KMT2AL3MBTL1 | |
| SCHEMBL7395344 | 0.91 | EDNRA (0.81) | EDNRAMAGI3ERAP2KMT2AL3MBTL1 | |
| SCHEMBL7397165 | 0.90 | EDNRA (0.73) | EDNRAMAGI3CASP1CASP3CASP4 | |
| SCHEMBL30533192 | 0.90 | EDNRA (0.73) | EDNRAMAGI3CASP1CASP3CASP4 | |
| SCHEMBL7400886 | 0.89 | EDNRA (0.76) | EDNRAMAGI3CASP1CASP3CASP4 | |
| SCHEMBL7400884 | 0.89 | EDNRA (0.76) | EDNRAMAGI3CASP1CASP3CASP4 | |
| SCHEMBL30533193 | 0.89 | EDNRA (0.84) | EDNRAMAGI3CASP1CASP3CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | claimed |
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | claimed |