Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853682 | 0.86 | GSK3B (0.42) | GSK3AGSK3BELANETSHRABL1 | |
| Hydrochloric Acid SCHEMBL4133179 | 0.85 | GSK3A (0.41) | GSK3AGSK3BELANETSHRABL1 | |
| SCHEMBL9708708 | 0.84 | GSK3A (0.49) | GSK3AGSK3BELANETSHRABL1 | |
| SCHEMBL25551959 | 0.83 | TSHR (0.36) | GSK3AGSK3BELANETSHRKMT2A | |
| SCHEMBL668453 | 0.81 | TSHR (0.56) | GSK3AGSK3BELANETSHRKMT2A | |
| SCHEMBL6528311 | 0.80 | TSHR (0.50) | GSK3AGSK3BELANETSHRKMT2A | |
| SCHEMBL6495319 | 0.78 | TSHR (0.49) | GSK3AGSK3BELANETSHRKMT2A | |
| SCHEMBL13775361 | 0.78 | GSK3B (0.41) | GSK3AGSK3BELANETSHRABL1 | |
| SCHEMBL16424936 | 0.78 | TSHR (0.49) | GSK3AGSK3BELANETSHRABL1 | |
| Hydrochloric Acid SCHEMBL4118546 | 0.77 | GSK3B (0.40) | GSK3AGSK3BELANETSHRABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211183-B1 | PIPERAZINE DERIVATIVE ANTICOAGULANTS; ANTIISCHEMIC AGENTS; CARDIOVASCULAR DISORDERS | COR THERAPEUTICS, INC. | 2001-04-03 | — | — | US | disclosed |
| EP-0975625-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046591-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |