Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9282013 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTPKMGFERSMN1; SMN2 | |
| SCHEMBL7399390 | 0.84 | MAPT (0.45) | ALDH1A1MAPTPKMGFERSMN1; SMN2 | |
| SCHEMBL7401011 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MAPTPKMGFERSMN1; SMN2 | |
| SCHEMBL7399572 | 0.81 | MAPT (0.46) | ALDH1A1MAPTPKMGFERSMN1; SMN2 | |
| SCHEMBL7400122 | 0.81 | KMT2A (0.51) | ALDH1A1MAPTPKMTSHRLMNA | |
| SCHEMBL9282010 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPTPKMGFERSMN1; SMN2 | |
| SCHEMBL7400434 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MAPTPKMGFERSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8837988 | 0.71 | ALDH1A1 (0.57) | ALDH1A1MAPTPKMGFERSMN1; SMN2 | |
| SCHEMBL8837972 | 0.71 | HRH3 (0.57) | — | |
| Hydrochloric Acid SCHEMBL8838070 | 0.71 | HRH3 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |